Comparative Effectiveness Research (CER)

The IOM defines CER as the generation and synthesis of evidence that compares the benefits and harms of alternative methods to prevent, diagnose, treat and monitor a clinical condition, or to improve the delivery of care. The purpose of CER is to assist consumers, clinicians, purchasers, and policy makers to make informed decisions that will improve health care at both the individual and population levels.

Dr. Richard Boyce is one of four scholars in the AHRQ-funded University of Pittsburgh's Comparative Effectiveness Research Program Scholars Program. As part of his training, he is conducting research to compare the effectiveness and safety of antidepressants used to treat elderly adults residing in nursing homes. The aims of the study include a systematic review of antidepressant use in nursing homes and two observational cohort studies using electronic medical records in UPMC nursing homes. This newly-approved study, titled "The comparative effectiveness and safety of antidepressants for the treatment of depression in nursing home residents", will apply methods from comparative effectiveness research, pharmacoepidemiology, and biomedical informatics.  His mentoring team includes DBMI faculty Dr. Steven Handler and Dr. Roger Day along with Drs. Joseph Hanlon (Geriatrics), Stephanie Studenski (Geriatrics), and Sally Morton (Biostatistics).  Funding is provided by K12 funding from the Agency for Healthcare Research and Quality. Grant# K12 HS019461-01 — “The University of Pittsburgh's Comparative Effectiveness Research Scholars Program“

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